Investigation by scintigraphic methods of platelet kinetics under normal and septic shock conditions in the experimental baboon model.
Identifieur interne : 005602 ( Main/Exploration ); précédent : 005601; suivant : 005603Investigation by scintigraphic methods of platelet kinetics under normal and septic shock conditions in the experimental baboon model.
Auteurs : RBID : pubmed:2252607English descriptors
- KwdEn :
- Animals, Blood Platelets (physiology), Disease Models, Animal, Escherichia coli Infections (blood), Escherichia coli Infections (radionuclide imaging), Indium Radioisotopes (diagnostic use), Liver (radionuclide imaging), Lung (radionuclide imaging), Male, Neutrophils (physiology), Papio, Platelet Activation, Respiratory Distress Syndrome, Adult (blood), Respiratory Distress Syndrome, Adult (radionuclide imaging), Shock, Septic (blood), Shock, Septic (radionuclide imaging), Spleen (radionuclide imaging).
- MESH :
- chemical , diagnostic use : Indium Radioisotopes.
- blood : Escherichia coli Infections, Respiratory Distress Syndrome, Adult, Shock, Septic.
- physiology : Blood Platelets, Neutrophils.
- radionuclide imaging : Escherichia coli Infections, Liver, Lung, Respiratory Distress Syndrome, Adult, Shock, Septic, Spleen.
- Animals, Disease Models, Animal, Male, Papio, Platelet Activation.
Abstract
This study concerned the correlation of platelet kinetics with the pathogenic course of septic shock and adult respiratory distress syndrome (ARDS) in the anesthetised baboon model. 111In-tropolonate platelets were traced in vivo in normal baboons (n = 7) and in Escherichia coli-infected baboons, which were reinjected with the labeled autologous platelets either 2 hr after the onset of the E. coli infusion (procedure A: n = 4) or simultaneously with the infusion (procedure B; n = 3). One minute images were taken hourly for 5 hr, using a gamma camera and data processor. Time-activity curves were obtained for platelet clearance from the blood and the lungs and for platelet accumulation in the liver and spleen. A significant retention of platelets in the lungs of baboons with E. coli-induced septic shock was noted, as well as an accelerated clearance from the circulation. Platelets were distributed mainly to the spleen after induction of bacteremia, later substantially moved to the liver, and even later moved back to the spleen.
PubMed: 2252607
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Investigation by scintigraphic methods of platelet kinetics under normal and septic shock conditions in the experimental baboon model.</title><author><name sortKey="Dormehl, I C" uniqKey="Dormehl I">I C Dormehl</name><affiliation wicri:level="1"><nlm:affiliation>AEC Institute for Life Sciences, Faculty of Medicine, University of Pretoria, South Africa.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>AEC Institute for Life Sciences, Faculty of Medicine, University of Pretoria</wicri:regionArea></affiliation></author><author><name sortKey="Kilian, J G" uniqKey="Kilian J">J G Kilian</name></author><author><name sortKey="Maree, M" uniqKey="Maree M">M Maree</name></author><author><name sortKey="Jacobs, L" uniqKey="Jacobs L">L Jacobs</name></author></titleStmt><publicationStmt><date when="1990">1990</date><idno type="RBID">pubmed:2252607</idno><idno type="pmid">2252607</idno><idno type="wicri:Area/Main/Corpus">005B15</idno><idno type="wicri:Area/Main/Curation">005B15</idno><idno type="wicri:Area/Main/Exploration">005602</idno></publicationStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Blood Platelets (physiology)</term><term>Disease Models, Animal</term><term>Escherichia coli Infections (blood)</term><term>Escherichia coli Infections (radionuclide imaging)</term><term>Indium Radioisotopes (diagnostic use)</term><term>Liver (radionuclide imaging)</term><term>Lung (radionuclide imaging)</term><term>Male</term><term>Neutrophils (physiology)</term><term>Papio</term><term>Platelet Activation</term><term>Respiratory Distress Syndrome, Adult (blood)</term><term>Respiratory Distress Syndrome, Adult (radionuclide imaging)</term><term>Shock, Septic (blood)</term><term>Shock, Septic (radionuclide imaging)</term><term>Spleen (radionuclide imaging)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="diagnostic use" xml:lang="en"><term>Indium Radioisotopes</term></keywords><keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Escherichia coli Infections</term><term>Respiratory Distress Syndrome, Adult</term><term>Shock, Septic</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Blood Platelets</term><term>Neutrophils</term></keywords><keywords scheme="MESH" qualifier="radionuclide imaging" xml:lang="en"><term>Escherichia coli Infections</term><term>Liver</term><term>Lung</term><term>Respiratory Distress Syndrome, Adult</term><term>Shock, Septic</term><term>Spleen</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Disease Models, Animal</term><term>Male</term><term>Papio</term><term>Platelet Activation</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">This study concerned the correlation of platelet kinetics with the pathogenic course of septic shock and adult respiratory distress syndrome (ARDS) in the anesthetised baboon model. 111In-tropolonate platelets were traced in vivo in normal baboons (n = 7) and in Escherichia coli-infected baboons, which were reinjected with the labeled autologous platelets either 2 hr after the onset of the E. coli infusion (procedure A: n = 4) or simultaneously with the infusion (procedure B; n = 3). One minute images were taken hourly for 5 hr, using a gamma camera and data processor. Time-activity curves were obtained for platelet clearance from the blood and the lungs and for platelet accumulation in the liver and spleen. A significant retention of platelets in the lungs of baboons with E. coli-induced septic shock was noted, as well as an accelerated clearance from the circulation. Platelets were distributed mainly to the spleen after induction of bacteremia, later substantially moved to the liver, and even later moved back to the spleen.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">2252607</PMID><DateCreated><Year>1991</Year><Month>01</Month><Day>22</Day></DateCreated><DateCompleted><Year>1991</Year><Month>01</Month><Day>22</Day></DateCompleted><DateRevised><Year>2003</Year><Month>11</Month><Day>14</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0885-8276</ISSN><JournalIssue CitedMedium="Print"><Volume>5</Volume><Issue>2</Issue><PubDate><Year>1990</Year></PubDate></JournalIssue><Title>American journal of physiologic imaging</Title><ISOAbbreviation>Am J Physiol Imaging</ISOAbbreviation></Journal><ArticleTitle>Investigation by scintigraphic methods of platelet kinetics under normal and septic shock conditions in the experimental baboon model.</ArticleTitle><Pagination><MedlinePgn>75-9</MedlinePgn></Pagination><Abstract><AbstractText>This study concerned the correlation of platelet kinetics with the pathogenic course of septic shock and adult respiratory distress syndrome (ARDS) in the anesthetised baboon model. 111In-tropolonate platelets were traced in vivo in normal baboons (n = 7) and in Escherichia coli-infected baboons, which were reinjected with the labeled autologous platelets either 2 hr after the onset of the E. coli infusion (procedure A: n = 4) or simultaneously with the infusion (procedure B; n = 3). One minute images were taken hourly for 5 hr, using a gamma camera and data processor. Time-activity curves were obtained for platelet clearance from the blood and the lungs and for platelet accumulation in the liver and spleen. A significant retention of platelets in the lungs of baboons with E. coli-induced septic shock was noted, as well as an accelerated clearance from the circulation. Platelets were distributed mainly to the spleen after induction of bacteremia, later substantially moved to the liver, and even later moved back to the spleen.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Dormehl</LastName><ForeName>I C</ForeName><Initials>IC</Initials><Affiliation>AEC Institute for Life Sciences, Faculty of Medicine, University of Pretoria, South Africa.</Affiliation></Author><Author ValidYN="Y"><LastName>Kilian</LastName><ForeName>J G</ForeName><Initials>JG</Initials></Author><Author ValidYN="Y"><LastName>Maree</LastName><ForeName>M</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Jacobs</LastName><ForeName>L</ForeName><Initials>L</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType>Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>DENMARK</Country><MedlineTA>Am J Physiol Imaging</MedlineTA><NlmUniqueID>8610225</NlmUniqueID><ISSNLinking>0885-8276</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance>Indium Radioisotopes</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Blood Platelets</DescriptorName><QualifierName MajorTopicYN="Y">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Disease Models, Animal</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Escherichia coli Infections</DescriptorName><QualifierName MajorTopicYN="N">blood</QualifierName><QualifierName MajorTopicYN="Y">radionuclide imaging</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Indium Radioisotopes</DescriptorName><QualifierName MajorTopicYN="N">diagnostic use</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Liver</DescriptorName><QualifierName MajorTopicYN="N">radionuclide imaging</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Lung</DescriptorName><QualifierName MajorTopicYN="N">radionuclide imaging</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Neutrophils</DescriptorName><QualifierName MajorTopicYN="N">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Papio</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Platelet Activation</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Respiratory Distress Syndrome, Adult</DescriptorName><QualifierName MajorTopicYN="N">blood</QualifierName><QualifierName MajorTopicYN="Y">radionuclide imaging</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Shock, Septic</DescriptorName><QualifierName MajorTopicYN="N">blood</QualifierName><QualifierName MajorTopicYN="Y">radionuclide imaging</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Spleen</DescriptorName><QualifierName MajorTopicYN="N">radionuclide imaging</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1990</Year><Month>1</Month><Day>1</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1990</Year><Month>1</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1990</Year><Month>1</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">2252607</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=IndiumV2/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 005602 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 005602 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= *** parameter Area/wikiCode missing ***
|area= IndiumV2
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:2252607
|texte= Investigation by scintigraphic methods of platelet kinetics under normal and septic shock conditions in the experimental baboon model.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:2252607" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a IndiumV2
| This area was generated with Dilib version V0.5.76. |  |